Which of the following is NOT a TNF alpha inhibitor?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Which of the following is NOT a TNF alpha inhibitor?

Explanation:
TNF-alpha inhibitors work by blocking the activity of tumor necrosis factor-alpha, a key driver of inflammation. Infliximab and adalimumab are antibodies that bind TNF-alpha, preventing it from signaling. Etanercept is a fusion protein that acts as a decoy receptor, sequestering TNF-alpha (and TNF-beta) away from its receptors. Tocilizumab, on the other hand, targets the IL-6 receptor, blocking IL-6 signaling rather than TNF-alpha. Therefore, tocilizumab is not a TNF-alpha inhibitor.

TNF-alpha inhibitors work by blocking the activity of tumor necrosis factor-alpha, a key driver of inflammation. Infliximab and adalimumab are antibodies that bind TNF-alpha, preventing it from signaling. Etanercept is a fusion protein that acts as a decoy receptor, sequestering TNF-alpha (and TNF-beta) away from its receptors. Tocilizumab, on the other hand, targets the IL-6 receptor, blocking IL-6 signaling rather than TNF-alpha. Therefore, tocilizumab is not a TNF-alpha inhibitor.

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