Which joints are most commonly involved early in Ankylosing Spondylitis?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Which joints are most commonly involved early in Ankylosing Spondylitis?

Explanation:
In Ankylosing Spondylitis, inflammation tends to start in the axial skeleton, with the sacroiliac joints being the most affected early. This sacroiliitis reflects enthesitis at the SI joints and underlies the classic inflammatory back pain seen in early disease—morning stiffness that improves with activity and tends to be worse after rest. While peripheral joints like knees, elbows, and shoulders can become involved, they’re not the initial or most common early sites. Therefore, the sacroiliac joints are the first and most characteristic joints affected.

In Ankylosing Spondylitis, inflammation tends to start in the axial skeleton, with the sacroiliac joints being the most affected early. This sacroiliitis reflects enthesitis at the SI joints and underlies the classic inflammatory back pain seen in early disease—morning stiffness that improves with activity and tends to be worse after rest. While peripheral joints like knees, elbows, and shoulders can become involved, they’re not the initial or most common early sites. Therefore, the sacroiliac joints are the first and most characteristic joints affected.

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