Which joint is most commonly affected in disseminated gonococcal infection?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Which joint is most commonly affected in disseminated gonococcal infection?

Explanation:
When Neisseria gonorrhoeae enters the bloodstream in disseminated gonococcal infection, it most often seeds large, highly vascularized joints. The knee stands out as the joint most commonly involved because of its large synovial cavity and abundant blood flow, making it the prime target for hematogenous spread. Clinically, DGI frequently presents with septic arthritis of the knee, though the wrists and ankles can be involved as well. In contrast, involvement of the spine or hip is less common, and small joints like the hand/wrist occur less often than the knee.

When Neisseria gonorrhoeae enters the bloodstream in disseminated gonococcal infection, it most often seeds large, highly vascularized joints. The knee stands out as the joint most commonly involved because of its large synovial cavity and abundant blood flow, making it the prime target for hematogenous spread. Clinically, DGI frequently presents with septic arthritis of the knee, though the wrists and ankles can be involved as well. In contrast, involvement of the spine or hip is less common, and small joints like the hand/wrist occur less often than the knee.

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