Which comorbidity is commonly seen with DISH?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Which comorbidity is commonly seen with DISH?

Explanation:
DISH shows abnormal calcification and ossification of ligaments and entheses, and this process often occurs alongside metabolic disorders. The association with type 2 diabetes mellitus is the strongest and most consistently observed, likely reflecting insulin resistance and metabolic syndrome that contribute to increased ossification at ligament insertions. Hyperinsulinemia and related metabolic disturbances can promote osteoblastic activity at these sites, leading to the characteristic flowing anterior spinal ossifications seen in DISH. The other conditions listed do not have as clear a link to DISH, so they’re less commonly seen comorbidities in this context.

DISH shows abnormal calcification and ossification of ligaments and entheses, and this process often occurs alongside metabolic disorders. The association with type 2 diabetes mellitus is the strongest and most consistently observed, likely reflecting insulin resistance and metabolic syndrome that contribute to increased ossification at ligament insertions. Hyperinsulinemia and related metabolic disturbances can promote osteoblastic activity at these sites, leading to the characteristic flowing anterior spinal ossifications seen in DISH. The other conditions listed do not have as clear a link to DISH, so they’re less commonly seen comorbidities in this context.

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