Which cells lie along bone surfaces and serve as precursors to osteoblasts?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Which cells lie along bone surfaces and serve as precursors to osteoblasts?

Explanation:
Osteoprogenitor cells sit on bone surfaces and act as the source for new osteoblasts. These osteogenic cells line the periosteum and endosteum and arise from mesenchymal stem cells. When bone formation or remodeling is needed, they proliferate and differentiate into osteoblasts, which then synthesize new bone matrix. Osteoblasts themselves can become embedded and mature into osteocytes, while chondrocytes are cartilage cells not directly involved in forming bone surfaces. So, the cells at bone surfaces that serve as precursors to osteoblasts are osteoprogenitor cells.

Osteoprogenitor cells sit on bone surfaces and act as the source for new osteoblasts. These osteogenic cells line the periosteum and endosteum and arise from mesenchymal stem cells. When bone formation or remodeling is needed, they proliferate and differentiate into osteoblasts, which then synthesize new bone matrix. Osteoblasts themselves can become embedded and mature into osteocytes, while chondrocytes are cartilage cells not directly involved in forming bone surfaces. So, the cells at bone surfaces that serve as precursors to osteoblasts are osteoprogenitor cells.

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