Which best describes treatment of Myalgic Encephalomyelitis?

• A. Antivirals
• B. Immunosuppressants
• C. Supportive care with cognitive behavioral therapy and low-impact exercises
• D. High-dose steroids

Answer: (C)

There isn’t a disease-modifying therapy for ME/CFS, so management focuses on relieving symptoms and preserving function. The best-supported approach combines supportive care with strategies to manage energy and improve quality of life. Cognitive behavioral therapy helps patients cope with the chronic illness and guides them in pacing activities to avoid triggering post-exertional malaise, while low‑impact, gradually graded exercise is used carefully to maintain fitness without worsening symptoms. Antivirals, immunosuppressants, or high‑dose steroids do not have proven benefit for typical ME/CFS and aren’t routinely used unless another specific condition is identified. In short, this patient-centered plan emphasizes symptom management, pacing, and gentle activity, rather than altering the disease with broad pharmacologic therapies.