Serum Protein Electrophoresis measures immunoglobulins along with which other plasma proteins?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Serum Protein Electrophoresis measures immunoglobulins along with which other plasma proteins?

Explanation:
Serum protein electrophoresis separates the major fractions of serum proteins into albumin and globulins. Immunoglobulins are a key part of the globulin fraction, especially the gamma globulins. Because the test uses serum (not plasma), fibrinogen is not present and thus not measured. Hemoglobin and platelets are not serum proteins at all; hemoglobin is inside red blood cells and platelets are cellular elements. Therefore the test profiles the major serum proteins—albumin and globulins—with immunoglobulins forming part of the globulin group.

Serum protein electrophoresis separates the major fractions of serum proteins into albumin and globulins. Immunoglobulins are a key part of the globulin fraction, especially the gamma globulins. Because the test uses serum (not plasma), fibrinogen is not present and thus not measured. Hemoglobin and platelets are not serum proteins at all; hemoglobin is inside red blood cells and platelets are cellular elements. Therefore the test profiles the major serum proteins—albumin and globulins—with immunoglobulins forming part of the globulin group.

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