Lesinurad belongs to which drug class?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Lesinurad belongs to which drug class?

Explanation:
Lesinurad lowers serum urate by blocking the URAT1 transporter in the proximal tubule of the kidney, which reduces reabsorption of uric acid and increases its excretion in urine. This makes it a URAT1 transporter inhibitor, a type of uricosuric agent that specifically targets URAT1. It is not a xanthine oxidase inhibitor, which would decrease uric acid production, nor a uricase enzyme, which would enzymatically degrade uric acid.

Lesinurad lowers serum urate by blocking the URAT1 transporter in the proximal tubule of the kidney, which reduces reabsorption of uric acid and increases its excretion in urine. This makes it a URAT1 transporter inhibitor, a type of uricosuric agent that specifically targets URAT1. It is not a xanthine oxidase inhibitor, which would decrease uric acid production, nor a uricase enzyme, which would enzymatically degrade uric acid.

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