In vitamin D metabolism, which metabolite is stored in the liver as storage form?

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Multiple Choice

In vitamin D metabolism, which metabolite is stored in the liver as storage form?

Explanation:
The key idea is that the liver stores vitamin D as a 25-hydroxylated metabolite, 25(OH)D. This form serves as the body's reservoir and is the circulating pool from which the kidney can produce the active hormone when needed. The 25-hydroxy forms (whether from vitamin D2 or D3) are storage-ready, whereas the 1,25-dihydroxy forms are the hormonally active versions and are not stored long-term. In this set, the option that represents the storage form is 25(OH) vitamin D2. Remember that both 25(OH)D2 and 25(OH)D3 reflect stored vitamin D, but the 25-hydroxy form in general is the storage metabolite, not the active 1,25(OH) forms.

The key idea is that the liver stores vitamin D as a 25-hydroxylated metabolite, 25(OH)D. This form serves as the body's reservoir and is the circulating pool from which the kidney can produce the active hormone when needed. The 25-hydroxy forms (whether from vitamin D2 or D3) are storage-ready, whereas the 1,25-dihydroxy forms are the hormonally active versions and are not stored long-term.

In this set, the option that represents the storage form is 25(OH) vitamin D2. Remember that both 25(OH)D2 and 25(OH)D3 reflect stored vitamin D, but the 25-hydroxy form in general is the storage metabolite, not the active 1,25(OH) forms.

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