Calcium pyrophosphate crystals show which type of birefringence?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Calcium pyrophosphate crystals show which type of birefringence?

Explanation:
Calcium pyrophosphate crystals exhibit positive birefringence, which is a hallmark of their light-splitting properties under polarized microscopy. These crystals are typically rhomboid and, when viewed with a first-order red compensator, align so that parallel to the slow optical axis they appear blue. This positive sign contrasts with monosodium urate crystals (gout), which are negatively birefringent and appear yellow when parallel. Remembering that CPPD crystals are rhomboid and show blue with parallel alignment helps you identify them as positively birefringent.

Calcium pyrophosphate crystals exhibit positive birefringence, which is a hallmark of their light-splitting properties under polarized microscopy. These crystals are typically rhomboid and, when viewed with a first-order red compensator, align so that parallel to the slow optical axis they appear blue. This positive sign contrasts with monosodium urate crystals (gout), which are negatively birefringent and appear yellow when parallel. Remembering that CPPD crystals are rhomboid and show blue with parallel alignment helps you identify them as positively birefringent.

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