Calcitonin is secreted by which cells?

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Prepare for the CMS II Rheumatology E1 Exam with our comprehensive quiz. Study using flashcards and multiple-choice questions, each with hints and explanations. Get ready for success!

Multiple Choice

Calcitonin is secreted by which cells?

Explanation:
Calcitonin is secreted by specialized thyroid cells called parafollicular cells, or C cells. These cells release calcitonin in response to high blood calcium, and the hormone lowers calcium levels mainly by inhibiting osteoclast-mediated bone resorption. This makes thyroid C cells the source. Pancreatic islet cells secrete insulin and glucagon; osteoclasts are bone-resorbing cells but do not produce calcitonin; parathyroid chief cells secrete PTH, which raises calcium levels.

Calcitonin is secreted by specialized thyroid cells called parafollicular cells, or C cells. These cells release calcitonin in response to high blood calcium, and the hormone lowers calcium levels mainly by inhibiting osteoclast-mediated bone resorption. This makes thyroid C cells the source. Pancreatic islet cells secrete insulin and glucagon; osteoclasts are bone-resorbing cells but do not produce calcitonin; parathyroid chief cells secrete PTH, which raises calcium levels.

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